Unique Cytoplasmic Membranes in Rous Sarcoma Virus-induced Tumors of a Subhuman Primate

Although the natural host of the Rous sarcoma virus (RSV) is the chicken, many strains of the virus have induced tumors in various mammals. Recently, a New World monkey, the marmoset (Saquinus sp.), was added to the list of animals susceptible to RSV oncogenesis (1). This report deals with a unique membranous cytoplasmic structure found in cells from two intracerebral and four subcutaneous tumors which developed following neonatal inoculation with the SchmidtRuppin strain of RSV.